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Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic materia...
Do Alternative Therapies Have a Role in Autism?
Ayurveda Homoeopathy Hyperbaric therapy Autism Behavioral therapy Occupational therapy Yoga
2015/7/15
Interventions considered to be branches of Complementary & Alternative Medicine (CAM) for autism are on the rise. Many new treatments have emerged & traditional beliefs of Ayurveda, Yoga, Behavioral t...
FUNCTIONAL GENOMICS STUDY TO UNDERSTAND THE ROLE OF SEROTONIN IN MOUSE EMBRYONIC STEM CELLS
Serotonin mouse embryonic stem cells
2015/5/26
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that is synthesized from the amino acid L-tryptophan and is reported to localize in mitochondria of embryonic stem cells. Even bef...
ROLE OF OVARIAN CANCER-INITIATING CELLS IN HIGH-GRADE SEROUS OVARIAN CARCINOGENESIS
Epigenetics DNA Methylation Carcinogenesis
2015/5/26
A subpopulation of tumor cells known as ovarian cancer initiating cells (OCICs) have been shown to be the cells that propagate the tumor phenotype in ovarian cancer. Studies have showed that a very sm...
Rap1a and Rap1b are two closely related members of the Ras family of small GTPases. Despite their high sequence similarity, the two proteins serve non-redundant functions in cells and organs. Rap1a pl...
The Regulatory Role Of Matrix Metalloproteinases In T Cell Activation
T cell activation MMP9 Matrix Metalloproteinases
2015/5/25
Introduction: Matrix metalloproteinases (MMPs) are known for their role in extracellular matrix remodeling, but their role in regulating intracellular immune cell function is unknown. We reported that...
DIFFERENTIAL ROLE OF PI-3KINASE p85 (α & β) REGULATORY SUBUNITS IN MAST CELL DEVELOPMENT
Cell cycle -- Regulation Enzymes
2015/5/25
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
THE ROLE OF CERAMIDES IN CIGARETTE SMOKE-INDUCED ALVEOLAR CELL DEATH
The complex pathogenesis emphysema involves disappearance
2015/5/25
The complex pathogenesis of emphysema involves disappearance of alveolar structures, in part attributed to alveolar cell apoptosis. The mechanism by which cigarette smoke (CS) induces alveolar cell ap...
The role of SWI/SNF in regulating smooth muscle differentiation
Brm smooth muscle knockout
2015/5/22
There are many clinical diseases involving abnormal differentiation of smooth muscle, such as atherosclerosis, hypertension and asthma. In these diseases, one important pathological process is the dis...
Anatomy and physiology of the mineralized tissues: Role in the pathogenesis of osteoarthrosis
bone calicified cartilage
2014/12/4
Synovial joints are composed of several different kinds of tissue that interact to protect normal joint function. Three subchondral mineralized tissues can be identified – calcified cartilage, subchon...
Exploring Correlation Between Perceived Parenting Styles, Early Maladaptive Schemas, and Depression Among Women With Depressive Symptoms in Iran and India- Role of Early Maladaptive Schemas as Mediators and Moderatos
Schemas Depression Women Parenting Iran India
2015/10/16
Background: Many studies have reported that inadequate parental styles can contribute to depressive symptoms through dysfunctional cognitive styles.
Protective Role of Endogenous Ovarian Hormones Against Learning and Memory Impairments and Brain Tissues Oxidative Damage Induced by Lipopolysaccharide
Learning Memory Ovariectomy Lipopolysaccharide Oxidative Stress
2015/10/12
Background:: The contribution of neuroinflammation in Alzheimer’s disease (AD) has been widely reported. The effects of female gonadal hormones in both neuroinflammation and brain cognitive functions ...
Chemotaxis is defined as the unidirectional movement of a cell in response to a chemical gradient in the direction from a low to a high concentration of chemoattractant.
The Role of Affects in Culture-Based Interventions: Implications for Practice
Cultural-Based Intervention Affective Semiosis PLS Path Modeling
2013/2/20
The study aimed to show the relevance of two types of sense-making processes (i.e. cognitive and affective) in culture-based interventions. A hierarchical model based on a psychodynamic theoretical fr...
The Role of Insects in Mechanical Transmission of Human Parasites
Insects Mechanical Transmission Human Parasites
2015/9/23
Arthropods are probably the most successful of all animals. They are found in every type of habitat and in all regions of the world. Without the vector, the parasite life cycle would be broken and the...