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VALPROIC ACID TRANSFER ACROSS HUMAN PLACENTAL COTYLEDON DURING DUAL PERFUSION IN VITRO
valproic acid placental transfer human pregnancy
2010/12/22
Valproic acid (VPA) is a well-known antiepileptic drug with a signifi cant teratogenic effect when administered during pregnancy. To investigate the transplacental transport of VPA, we used an in vitr...
Effects of a dopamine receptor agonist and atropine sulfate on absorption of valproic acid in rats
dopamine receptor absorption valproic acid rats
2009/5/8
The aim of this study is to determine whether pramipexole hydrochloride hydrate (PHH) and atropine sulfate affect valproic acid (VPA) pharmacokinetics and to evaluate how plasma VPA concentrations a...
SIMPLE AND RAPID GAS-CHROMATOGRAPHIC METHOD FOR QUANTITATION OF TOTAL AND FREE VALPROIC ACID IN HUMAN SERUM
Valproic acid gas-chromatography serum
2010/4/9
Valproic acid (VPA) is one of the mostly used antiepileptic drugs that may have some side effects so, it is highly recommended to evaluate its serum concentrations. The aim of this study was to develo...
SIMPLE AND RAPID GAS-CHROMATOGRAPHIC METHOD FOR QUANTITATION OF TOTAL AND FREE VALPROIC ACID IN HUMAN SERUM
Valproic acid gas-chromatography serum
2010/4/9
Valproic acid (VPA) is one of the mostly used antiepileptic drugs that may have some side effects so, it is highly recommended to evaluate its serum concentrations. The aim of this study was to develo...
Induction of liver metallothionein contribute to the developmental toxicity of valproic acid in rat
Teratogenicity Valproic acid Zinc Metallothionein
2010/2/5
There is an increased risk of neural tube defects and axial skeletal malformations among infants born by mothers who had received Valproic acid...The aim of the present study is, if administration of ...