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Expression and Clinical Significance of Tumor Necrosis Factor Receptor-Associated Factor 6 in Patients With Colon Cancer
Receptors Tumor Necrosis Factor Gene Expression Colonic Neoplasms
2016/1/26
Background: Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been reported to be highly expressed in many tumor tissues, but it is still of value to detect its expression in patients wit...
Tumor Necrosis Factor-Alpha Polymorphism and Susceptibility to Multiple Sclerosis in the Iranian Population
Tumor Necrosis Factor-Alpha Multiple Sclerosis Sclerosis
2015/10/16
Background: Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology. Tumor necrosis factor-α (TNF-α) microsatellite as a proinflammatory cytokine is believed to play an important r...
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Mandibular necrosis in beagle dogs treated with bisphosphonates
osteonecrosis bisphosphonates
2014/12/4
Objectives – To test the effect of bisphosphonate (BP) treatment for up to 3 years on bone necrosis and osteocyte death in the mandible using a canine model. Materials and Methods –...
Mandible matrix necrosis in beagle dogs After 3-years of daily oral bisphosphonate treatment
osteonecrosis of the jaw remodeling suppression
2014/12/4
Purpose An increasing number of reports have implicated bisphosphonates as contributing to osteonecrosis of the jaw. The goal of this study was to evaluate mandible necrosis in beagle dogs treated for...
Tumor Necrosis Factor-Alpha Polymorphism at Position -238 in Preeclampsia
Tumor Necrosis Factor-Alpha Pre-Eclampsia Polymorphism Genetic
2015/10/10
Background:: Preeclampsia is the most common serious disorder during pregnancy and studies show several immune-related processes in its pathophysiology. The role of cytokines and their expression rema...
Conjunctival Necrosis and Scleritis Following Subtenon Triamcinolone Acetonide Injection
Conjunctival Necrosis Triamcinolone acetonate Subtenon Injection Complications Corticosteroids
2015/10/8
The present study aims to report a case of conjunctival necrosis and scleritis due to a subtenon injection of triamcinolone acetonate. A 15-year-old boy received a subtenon injection of triamcinolone ...
Segmental arterial mediolysis: A clinical-pathologic review, its role in fibromuscular dysplasia and description and differential diagnosis of the masquerader-muscular artery cystic necrosis
Segmental Arterial Mediolysis Norepinephrine Adrenergic Agonists
2013/2/19
Segmental arterial mediolysis (SAM) is an uncommon non-inflammatory iatrogenic arteriopathy caused by alpha-1 adrenergic agonists or Beta-2 agonists able to release norepinephrine from the peripheral ...
Interleukin-12 and Tumor Necrosis Factor-Β Gene Polymorphisms as Genetic Susceptibility Factors for Brucellosis in Iranian Patients
Brucella Genetic polymorphisms Interleukin-12 Tumor necrosis factor-β Iran
2015/9/21
cMethods: One hundred and ninety-six patients with brucellosis and 81 healthy farmers (controls) who owned infected animals and consumed their contaminated dairy products were included in this study. ...
Aseptic bone necrosis among U.S. Navy divers:survey of 934 nonrandomly selected personnel
Divers human Aseptic bone necrosis DCS
2009/7/20
Nine hundred thirty-four U.S. Navy divers were selected and surveyed radiographically using standard techniques developed for detecting aseptic bone necrosis (ABN). X rays were read by qualified radio...
Current status of tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) targeting cancer therapy
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) TRAIL receptor 1 (TRAIL-R1), TRAIL receptor 2 (TRAIL-R2) apoptosis KM mouseTM monoclonal antibody targeting therapeutics
2009/7/15
Monoclonal antibodies have already established a secure position as a very promising strategy for anti-tumor therapeutics. High specificity and high affinity are attractive characteristics of antibodi...
Posterior shoulder dislocation and humeral head necrosis in a recreational scuba diver with diabetes
diabetic scuba diver case report injury
2009/7/8
An insulin-dependent diabetic who was previously a recreational scuba diver suffered a posterior shoulder dislocation after a trivial injury and was subsequently found to have local necrosis of the hu...
Tumor Necrosis Factor-a and Interleukin-6 in Peritoneal Adhesion Formation
Peritoneal adhesion Tumor necrosis factor-a Interleukin-6
2009/7/2
This study was carried out to assess the role of tumor necrosis factor (TNF-a) and interleukin-6 (IL-6 ) in plasma and peritoneal fluid in higher rates of adhesion formation following standard bowel i...
Development of ELISA Systems for Measurement of Human Tumor Necrosis Factor-Alpha (TNF-a)
TNF-a,ELISA
2009/6/22
The aim of this study was to develop a human tumor necrosis factor alpha (hTNF-a) ELISA system because specific and sensitive measurement of low levels of circulating TNF-a is very important for enlig...
Hyperbaric oxygen as an adjunctive treatment for severe laryngeal necrosis: a report of nine consecutive cases
HBO hyperbaric laryngeal necrosis
2009/6/12
Laryngeal necrosis is a rare complication of therapeutic radiation, but when it does occur there is no established, definitive treatment and laryngectomy is frequently required. This report is a retro...