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ω-3 and ω-6 long-chain PUFAs and their enzymatic metabolites in neovascular eye diseases
lipid metabolism long-chain polyunsaturated fatty acid retinopathy of prematurity diabetic retinopathy age-related macular degeneration
2018/11/14
Neovascular eye diseases, including retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration, threaten the visual health of children and adults. Current treatment options...
Effect of plasma metabolites of (+)-catechin and quercetin on monocyte adhesion to human aortic endothelial cells
endothelial cell reactive oxygen species rats
2016/6/13
Flavonoids may exert their health benefit in cardiovascular
disease by modulating monocyte adhesion in the
inflammatory process of atherosclerosis. Most in vitro studies
used forms of flavonoids pr...
Influence of nutritional status on the pharmacokinetics of acetylsalicylic acid and its metabolites in children with autoimmune disease
nutritional status pharmacokinetics children
2016/5/30
It is unknown whether nutritional status associated
with autoimmune disease alters the pharmacokinetics of
acetylsalicylic acid (ASA) and its metabolites.
New computer model predicts gut metabolites to better understand gastrointestinal disease（图）
gastrointestinal disease computer
2014/12/1
MEDFORD/SOMERVILLE, Mass-- Tufts University School of Engineering researchers and collaborators from Texas A&M University have published the first research to use computational modeling to predict and...
Vitamin D Metabolites Inhibit Adipocyte Differentiation in 3T3-L1 Preadipocytes
3T3-L1 preadipocytes inhibition of differentiation
2014/11/7
The rising prevalence of obesity in the past 20 years underscores the need to
understand the biology and key regulatory processes involved in the
development of obesity. Adipogenesis, or the form...
The 14kDa Protein Molecule Isolated from Garlic Suppresses Indoleamine 2, 3-Dioxygenase Metabolites in Mononuclear Cells In vitro
Garlic Indoleamine 3-dioxygenase Proliferation Tryptophan
2009/12/11
A wide range of biological activities of garlic in vitro and in vivo have been verified including its antioxidant, antitumor and anti-inflammatory effects. Indoleamine 2,3-dioxygenase (IDO) is an enzy...
The 14kDa Protein Molecule Isolated from Garlic Suppresses Indoleamine 2, 3-Dioxygenase Metabolites in Mononuclear Cells In vitro
Garlic Indoleamine 3-dioxygenase Proliferation Tryptophan
2009/12/11
A wide range of biological activities of garlic in vitro and in vivo have been verified including its antioxidant, antitumor and anti-inflammatory effects. Indoleamine 2,3-dioxygenase (IDO) is an enzy...
Ischemia-Reperfusion Injury,Reactive Oxygen Metabolites,and the Surgeon
Ischemia-Reperfusion Injury Reactive Oxygen Metabolites
2009/7/3
Surgeons are confronted with ischemia-reperfusion (IR) injury more often than they anticipate. Hypoperfusion associated with hypotension and hypovolemia is probably the most common cause of non-occlus...
Addition of specific metabolites to bovine epididymal cell culture medium enhances survival and motility of cryopreserved sperm
specific metabolites bovine epididymal cell culture medium cryopreserved sperm
2008/12/25
We have developed a cell culture system of bovine epididymal epithelium in which cryopreserved bovine sperm motility was efficiently maintained for many hours. The culture conditions to maintain v...
Plasma vitamin B-6 forms and their relation to transsulfuration metabolites in a large, population-based study
Vitamin B-6 homocysteine cystathionine cysteine methylenetetrahydrofolate reductase transsulfuration
2008/12/17
Background: Vitamin B-6 exists in different forms; one of those forms, pyridoxal 5'-phosphate (PLP), serves a cofactor in many enzyme reactions, including the transsulfuration pathway, in which homocy...
Choline-related supplements improve abnormal plasma methionine-homocysteine metabolites and glutathione status in children with cystic fibrosis
Choline betaine phospholipids ratio of glutathione to glutathione disulfide GSH:GSSG cystic fibrosis
2008/12/12
Background: Liver triacylglycerol accumulation and oxidative stress are common in cystic fibrosis (CF) and also occur in choline deficiency. Previously, we showed an association between elevated plasm...
PULMONARY CYTOTOXICITY OF SECONDARY METABOLITES OF STACHYBOTRYS CHARTARUM (EHRENB.) HUGHES
damp indoor environment moulds Stachybotrys chartarum
2010/12/23
Damp dwellings represent suitable conditions for extended indoor moulds. A cellulolytic micromycete Stachybotrys chartarum (Ehrenb.) Hughes is considered to be a tertiary colonizer of surfaces in affe...
INDOOR FUNGI AND THEIR CILIOSTATIC METABOLITES
indoor environment filamentous fungi ciliostatic metabolites
2010/12/24
According to epidemiological studies, it is possible that some secondary metabolites of indoor airborne fungi could be responsible for health troubles which occupants suffer from. In our previous expe...
Effects of vitamin D metabolites on intestinal calcium absorption and bone turnover in elderly women
Elderly women vitamin D calcitriol calcium absorption bone turnover calcium intake 25-hydroxyvitamin D sunlight
2016/12/17
Background: The relative importance of vitamin D metabolites in the regulation of gut calcium absorption has not been well studied in elderly women living in an environment with abundant sunlight...