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The Ref-1 (also called APE or HAP1) protein is a bifunctional enzyme impacting on a wide variety of important cellular functions. It acts as a major member of the DNA base excision repair pathway. Mor...
Endocannabinoids (eCB) and interleukin 6 (IL-6) levels change during physical activity, thus suggesting their involvement in the modulation of exercise-related processes like inflammation and energy h...
目的观察奇壬醇对牛II 型胶原特异性淋巴细胞体内和体外的免疫调节作用,探讨奇壬醇对抗原特异性淋巴细胞的免疫抑制作用机制。方法将Wistar 大鼠随机分为对照组、模型组、奇壬醇组和泼尼松龙组。除对照组外,均复制胶原诱导关节炎大鼠模型,造模当天开始给药。造模30 d 后取脾脏和引流淋巴结,制备单细胞悬液,经体外培养48 h 后,ELISA法检测培养上清中干扰素-γ(IFN-γ)、白介素-10(IL-1...
There are various theories concerning the etiology of preeclampsia and eclampsia. According to one of these, the immunologic mechanism may play a role. The aim of this study was to determine whether o...
During the last decade, several studies have focused on the adverse effects on health caused by exposure to electromagnetic fields (EMF). Some epidemiological studies of workers exposed to EMF have sh...
Traditionally, allergic contact dermatitis (ACD) has been associated with the activity of Th1 lymphocytes that secrete interferon gamma. Recent evidence indicates that other cells.
A pilot study was undertaken to investigate the differences in oxidative DNA damage and 2-h DNA repair in peripheral lymphocytes between lung cancer patients and healthy subjects. Twenty-four lung ca...
Genetic biomonitoring of human populations exposed to potential mutagens/carcinogens can be performed using different genetic markers. Sister chromatid exchange (SCE) is one of the most extensively us...
Ciprofloxacin is a quinolone carboxylic acid derivative and is commonly used in medicine. The genotoxicity of ciprofloxacin was evaluated in cultured human peripheral blood lymphocytes in patients wit...
Sister chromatid exchange (SCE) and chromosomal aberration (CA) in peripheral lymphocytes have been widely used in assessing exposure to mutagens and carcinogens. One of the extensively studied genoto...
Benzene is a relatively common environmental and occupational contaminant with carcinogenic and clastogenic properties. Therefore, further understanding of the adverse effect of benzene is still a mat...
Ionizing radiation affects the expression of adhesive and co-stimulatory molecules in lymphocytes. The physiological function of cellular isoform of prion protein (PrPc) is little known.
专著信息 书名 AFP triggers hepatoma cells escaping from immune surveillance through altering the expression of Fas/FasL and tumor necrosis factor related apoptosis-inducing ligand and its receptor of lympho...
Common variable immunodeficiency (CVID) is the most common symptomatic primary antibody deficiency, characterized by reduced serum immunoglobulins levels and increased susceptibility to recurrent pyog...
Study objectives were to compare the numbers of lymphocytes and lymphocyte subpopulations in induced sputum from asthmatic patients and from healthy subjects, and to determine the effect of inhaled an...

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