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The Effects of Insulin-Like Growth Factor-1 Gene Therapy and Cell Transplantation on Rat Acute Wound Model
IGF-1 Gene Therapy Cell Transplantation Fibroblast Wound Healing
2015/10/15
Background: Wound healing is a complex process. Different types of skin cells, extracellular matrix and variety of growth factors are involved in wound healing. The use of recombinant growth factors i...
Insulin-Like Growth Factor (IGF-I) in Mauriac Syndrome or Diabetic Dwarfism
Insulin-Like Growth Factor Mauriac Syndrome
2009/6/26
Mauriac syndrome is characterized by the development of dwarfism, obesity and hepatomegaly in
patients with insulin dependent diabetes mellitus (1). Growth retardation and hepatomegaly in diabetes me...
Insulin -Like Growth Factor Binding Protein-I; a Rapid Detection of Amniotic Fluid Leakage after Amniocentesis
Amniocentesis amniotic leakage insulin-like growth factor binding protein– I (IGFBP-I)
2009/6/22
The aim of this study was to assess the diagnostic value of vaginal insulin-like growth factor binding protein-1 (IGFBP-I) in the detection of amniotic fluid leakage after amniocentesis. It includes 5...
Modulation of insulin-like growth factor-1 in the seminal plasma of infertile men
Modulation insulin-like growth factor-1 seminal plasma infertile men
2009/2/18
It has been suggested that insulin-like growth factor (IGF)-1 plays an important role in the regulation of spermatogenesis in the testes. In the present study, concentrations of total IGF-1 we...
Immunohistochemical localization of insulin-like growth factor I（IGF-I）in the rat epididymis
Immunohistochemical localization insulin-like growth factor I（IGF-I） rat epididymis
2009/2/12
The distribution of insulin-like growth factor I (IGF-I) was studied by immunohistochemistry during postnatal development of the rat epididymis. At 2 weeks the immunoreactivity was mainly located al...
Insulin-like growth factor 1, but not growth hormone, has in vitro proliferative effects on neonatal foreskin fibroblasts without affecting 5-alpha-reductase or androgen receptor activity
5-a-Reductase androgen receptor micropenis
2009/2/11
Clinical observation of patients with congenital growth hormone (GH) deficiency and Laron-type dwarfism suggests that factors such as GH or insulin-like growth factor 1 (IGF-1) might in addition to ...
Effects of insulin-like growth factor-I on androgen production by highly purified pubertal and adult rat Leydig cells
Somatomedin-C development steroidogenesis
2009/2/10
Leydig cells were isolated and purified from adult and midpubertal rats to study the effects of insulin-like growth factor-I (IGF-I) on steroidogenesis. Androgen production, as measured in Leydig ce...
Dental and Craniofacial Characteristics in a Patient with Leprechaunism Treated with Insulin-Like Growth Factor-I
Enlarged teeth Macroglossia Leprechaunism IGF-I Craniofacial morphology
2008/11/6
Leprechaunism is an autosomal recessive disease characterized by elfin-like faces, loss of glucose homeostasis, and severe insulin resistance. This disease is caused by inherited defects of the insuli...