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NEUROPROTECTIVE EFFECT OF THYROTROPIN-RELEASING HORMONE (TRH) AGAINST GLUTAMATE TOXICITY IN VITRO
Heterologous Receptor Downregulation PC12 Cell Culture GH-3 Cell Culture G alpha q/11 Hippocampal Slice Superfusion TRH Neuroprotection
2015/5/21
Acute and chronic activation of both ionotropic and metabotropic glutamate (glut) receptors is implicated in many neurodegenerative disorders including AD, dementia, epilepsy, stroke and neurotrauma. ...
Evaluation of Biochemical, Hematological and Histological Parameters in Non Diabetic and Diabetic Wistar Rats Fed with Monosodium Glutamate
MSG Glutamate Wistar Rat Diabetes
2013/1/29
The parenteral or oral administration of monosodium glutamate (MSG) has been reported to have a deleterious effect on the hypothalamic arcuate nucleus, which changes appetite control. This alteration ...
Microinjection of NMDA-type glutamate receptor agonist NMDA and antagonist D-AP-5 into the central nucleus of the amygdale alters water intake rather than food intake
NMDA受体 NMDA D-AP-5 杏仁中央核 食物摄取 水摄取
2012/6/28
目的探讨杏仁中央核中的N-甲基-D-天冬氨酸(NMDA)型谷氨酸受体对食物和水摄取的影响。方法不锈钢套管植入雄性Sprague-Dawley大鼠一侧杏仁中央核内,NMDA型谷氨酸受体激动剂原型物NMDA,或选择性NMDA受体拮抗剂D(?)-2-氨基-5-磷酰基戊酸(D-AP-5)微量注射入饱食和含水度正常的大鼠的杏仁中央核内。结果杏仁中央核内注射入8.50,17.00,或34.00 nmol NM...
Glutamate dehydrogenase and triose-phosphate-isomerase coding genes for detection and genetic characterization of Giardia lamblia in human feces by PCR and PCR-RFLP*
Giardia lamblia glutamate dehydrogenase triosephosphate isomerase PCR PCR-RFLP
2011/3/22
The purpose of this study was comparison of the glutamate dehydrogenase (gdh) and triose phosphate isomerase (tpi) genes for detection and genetic characterization of Giardia lamblia (G. lamblia) in h...
Effect of helium and heliox on glutamate decarboxylase activity
helium heliox air glutamate decarboxylase
2009/3/30
The activity of glutamate decarboxylase (GAD) in pure helium at 6.8 MPa was significantly enhanced when compared to GAD activity in air at 0.1 MPa (906 vs. 602 nmol.h-1.mg-1 protein, respectively). No...
Identification of Glutamate Receptors and Transporters in Mouse and Human Sperm
Uptake immunocytochemistry RT-PCR inhibitor
2008/12/22
-Aminobutyric acid (GABA) and glutamate (Glu) are considered as the predominant inhibitory and excitatory neurotransmitters in mammalian central nervous systems (CNS), respectively. The presence o...
Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study
Glutamate carboxypeptidase II GCPII folate homocysteine cognition gene polymorphisms
2008/12/17
Background: Glutamate carboxypeptidase II (GCPII) encodes for intestinal folate hydrolase and brain N-acetylated -linked acidic dipeptidase. Previous studies provided conflicting results on the effect...
Lack of Glutamate Transporter EAAC1 in the Epididymis of Infertile c-ros Receptor Tyrosine-Kinase Deficient Mice
Male reproductive tract gene chips sperm gamete biology cDNA arrays
2008/12/15
Transgenic male mice carrying inactive mutations of the receptor tyrosine kinase c-ros lack the caput epididymidis initial segment and are infertile because sperm volume regulation is compromised. Com...