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High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/12/4
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
High Bone Mass in Mice Lacking Cx37 Due to Defective Osteoclast Differentiation
gap junctions connexin37 osteoclast
2014/11/6
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Dynamin Forms a Src Kinase–sensitive Complex with Cbl and Regulates Podosomes and Osteoclast Activity
dynamin osteoclast activity
2014/11/6
Podosomes are highly dynamic actin-containing adhesion structures found in osteoclasts, macrophages, and Rous sarcoma virus (RSV)-transformed fibroblasts. After integrin engagement, Pyk2 recruits Src ...
Titanium Surface Roughness Accelerates RANKL-dependent Differentiation in the Osteoclast Precursor Cell Line,RAW264.7
Titanium Osteoclast Implant
2009/9/14
The present study was a molecular analysis of the initial differentiation of osteoclast precursor RAW264.7 cells on titanium specimens. RAW264.7 cell line was cultured on titanium specimens of which t...
Tissue Inhibitors of Metalloproteinases (TIMP-1 and TIMP-2) Stimulate Osteoclast Differentiation
tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) osteoclasts bone marrow culture
2009/5/21
Tissue inhibitor of metalloproteinases-1 (TIMP-1) and TIMP-2, originally known as intrinsic inhibitors of matrix metalloproteinases (MMPs), are now known as constitutive components in serum and have ...
Fms-like tyrosine kinase (Flt)-4 signaling participates in osteoclast differentiation in osteopetrotic (op/op) mice
Fms-like tyrosine kinase (Flt)-4 osteoclast differentiation osteopetrotic (op/op) mice
2009/5/8
Vascular endothelial growth factor (VEGF) induces osteoclast differentiation as well as neovascularization by binding to the fms-like tyrosine kinase (Flt)-1 and fetal liver kinase (Flk)-1 receptors...
Epidermal Growth Factor in Liposomes May Enhance Osteoclast Recruitment during Tooth Movement in Rats
EGF Liposome Osteoclasts Tooth movement Orthodontic movement
2008/11/6
Objective: To evaluate the effects of local administration of epidermal growth factor (EGF) located within liposomes on recruitment of osteoclasts during mechanical force in rats.Materials and Methods...
Th17 Cells and Rheumatoid Arthritis -From the Standpoint of Osteoclast Differentiation-
IL-17 IL-23 osteoclast receptor activator of NF-κB ligand (RANKL) rheumatoid arthritis (RA) T cell Th17
2010/11/17
Rheumatoid arthritis is a chronic disease that affects multiple joints. It is considered to be an autoimmune disease in which a T helper (Th)-1 type response has been implicated to play an important p...
