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A low-cost mechanical device for minimally invasive surgery
low-cost mechanical device minimally invasive surgery
2017/3/14
Surgeons can now use a new type of mechanical instrument to perform complex, minimally invasive procedures, also known as laparoscopic surgery, thanks to researchers and small business entrepreneurs f...
How Mechanical Force Triggers Blood Clotting at the Molecular Scale
Mechanical Forc Triggers Blood Clotting Molecular Scale
2016/8/23
Using a unique single-molecule force measurement tool, a research team has developed a clearer understanding of how platelets sense the mechanical forces they encounter during bleeding to initiate the...
Sex-Related Differences in Self-Paced All Out High-Intensity Intermittent Cycling:Mechanical and Physiological Responses
Oxygen uptake sexual dimorphism anaerobic power reserve
2016/7/7
The purpose of this study was to compare sex-related responses to a self-paced all out high-intensity intermittent exercise (HIIE). 9 women and 10 men were submitted to a maximal incremental test (to ...
Use of Ultrasound to Monitor Biceps Femoris Mechanical Adaptations after Injury in a Professional Soccer Player
Ultrasound imaging tissue mechanics therapeutic exercise muscle physiology/performance EMG Biomechanics/lower extremity
2016/3/11
This study examined the use of ultrasound to monitor changes in the long head of the biceps femoris (BF) architecture of aprofessional soccer player with acute first-time hamstring strain. The player ...
Familiarization Effects of an Elliptical All-out Test and the Wingate Test Based on Mechanical Power Indices
Adaptation anaerobic coordination practice reliability Wingate
2015/5/18
The Wingate all-out test (WAT) is commonly used to estimate anaerobic capabilities of athletes by using an upper or lower body cycle ergometer, however, a new test modality called elliptical all-out t...
Effects of High-Impact Mechanical Loading on Synovial Cell Cultures
Impulsive factor rheumatoid arthritis synovium MMP
2015/3/12
Cartilage metabolism in response to mechanical loading is an important subject in sports science and medicine. In animal studies high-impact exercise is known to stimulate bone adaptation and increase...
Mechanical property and biocompatibility of PLLA coated DCPD composite scaffolds
biomedical engineering scaffolds biomaterial tissue engineering
2015/1/12
Dicalcium phosphate dihydrate (DCPD) cements have been used for bone repair due to its excellent biocompatibility and resorbability. However, DCPD cements are typically weak and brittle. To overcome t...
Signaling Pathways Involved in Mechanical Stimulation and ECM Geometry in Bone Cells
Mechanical Stimulation Osteoblast ECM
2015/1/12
The proliferation and differentiation of osteoblasts are influenced by mechanical and geometrical growth environments. A specific aim of my thesis was the elucidation of signaling pathways involved in...
Effects of 1 to 3 years' treatment with alendronate on mechanical properties of the femoral shaft in a canine model: implications for subtrochanteric femoral fracture risk
subtrochanteric fractures femur bisphosphonates
2014/12/4
Bisphosphonate (BP) treatment used to prevent bone loss in postmenopausal osteoporosis has recently been implicated in an apparent increase in subtrochanteric femoral fractures. Previous work showed t...
Changes in non-enzymatic glycation and its association with altered mechanical properties following 1-year treatment with risedronate or alendronate
bisphosphonates alendronate animal models
2014/12/4
Summary One year of high-dose bisphosphonate (BPs) therapy in dogs allowed the increased accumulation of advanced glycation end-products (AGEs) and reduced postyield work-to-fracture of the cortical b...
Nanoscale Changes in Collagen are Reflected in Physical and Mechanical Properties of Bone at the Microscale in Diabetic Rats
Zucker diabetic Sprague–Dawley Atomic Force Microscopy Raman Spectroscopy
2014/12/4
Diabetes detrimentally affects the musculoskeletal system by stiffening the collagen matrix due to increased advanced glycation end products (AGEs). In this study, tibiae and tendon from Zucker diabet...
Heritability of Lumbar Trabecular Bone Mechanical Properties in Baboons
mechanical properties nonhuman primate skeletal genetics
2014/12/4
Genetic effects on mechanical properties have been demonstrated in rodents, but not confirmed in primates. Our aim was to quantify the proportion of variation in vertebral trabecular bone mechanical p...
Reference-Point Indentation Correlates with Bone Toughness Assessed Using Whole-Bone Traditional Mechanical Testing
bone mechanical testing material properties
2014/12/4
Traditional bone mechanical testing techniques require excised bone and destructive sample preparation. Recently, a cyclic-microindentation technique, reference-point indentation (RPI), was described ...
In vivo reference point indentation reveals positive effects of raloxifene on mechanical properties following six months of treatment in skeletally mature beagle dogs
bone remodeling bone mechanics osteoporosis treatments indentation
2014/12/4
Raloxifene treatment has been shown previously to positively affect bone mechanical properties following one year of treatment in skeletally mature dogs. Reference point indentation (RPI) can be used ...
Can Deterministic Mechanical Size Effects Contribute to Fracture and Microdamage Accumulation in Trabecular Bone?
microdamage biomechanics fracture
2014/12/4
Failure of bone under monotonic and cyclic loading is related to the bone mineral density, the quality of the bone matrix, and the evolution of microcracks. The theory of linear elastic fracture mecha...