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Inhibition of SARS-CoV-2 (Previously 2019-nCoV) Infection by a Highly Potent Pan-Coronavirus Fusion Inhibitor Targeting Its Spike Protein That Harbors a High Capacity to Mediate Membrane Fusion
Inhibition SARS-CoV-2 Pan-Coronavirus Fusion Inhibitor Targeting High Capacity Mediate Membrane Fusion
2020/6/12
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in Wuhan, China has posed a serious threat to global public health. To develop specific anti-coronavirus therapeuti...
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Fusion mechanism 2019-nCoV inhibitors targeting HR1 domain spike protein
2020/6/12
Very recently, a novel coronavirus, 2019-nCoV, emerged in Wuhan, China and then quickly spread worldwide, resulting in >17,388 confirmed cases and 361 deaths as of 3 February 2020, thus calling for th...
观察比较Admira Fusion和BEAUTIFIL Ⅱ两种复合树脂修复中老年患者中度颈部缺损患牙的短期临床疗效并分析其影响因素。方法:选取2016年9月~2017年3月于南方医院就诊的50例年龄介于50~80岁的中度颈部缺损患者为研究对象,分别采用Admira Fusion纳米树脂(A组)和BEAUTIFIL Ⅱ纳米树脂(B组)修复,随访修复成功率、边缘密合率、表面粗糙率、色泽协调率、菌斑指数...
Small-Molecule Hydrophobic Tagging Induced Degradation of HaloTag Fusion Proteins
Degradation of HaloTag Fusion Proteins Small-Molecule Hydrophobic Tagging
2014/11/25
The ability to regulate any protein of interest in living systems with small molecules remains a challenge. We hypothesized that appending a hydrophobic moiety to the surface of a protein would mimic ...
Construction of Recombinant Bacmid Containing M2e-Ctxb and Producing the Fusion Protein in Insect Cell Lines
Influenza Vaccines Baculovirus Cholera Toxin Subunit B
2015/10/10
Background:: Sequence variations in glycoproteins of influenza virus surface impel us to design new candidate vaccines yearly. Ectodomain of influenza M2 protein is a surface and highly conserved prot...
Labial Fusion Causing Coital and Voiding Difficulty in a Young Woman
Labial Fusion Labial Adhesion
2013/1/29
Adhesions of the labia are extremely rare in the reproductive population with only a few cases described in the literature. We report a young female patient with coital and voiding difficulty. The pat...
Does Disc Space Height of Fused Segment Affect Adjacent Disc Degeneration in Anterior Lumbar Interbody Fusion? A Radiological Study
Adjacent segment degeneration Anterior lumbar interbody fusion
2015/9/25
Background: The restoration of disc space height (DSH) is essential in anterior lumbar interbody fusion (ALIF), while it is unclear whether the reduction of DSH may alter the mechanical status and adv...
中国医学科学院实验血液学国家重点实验室王建祥课题组在Leukemia期刊上发表"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene"
血液学 国家重点实验室 王建祥 课题组 Leukemia期刊
2012/2/23
中国医学科学院实验血液学国家重点实验室王建祥课题组在在Leukemia期刊发表文章"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.”
Unilateral Fusion of a Mandibular Third Molar to a Supernumerary Tooth: A Case Report
Fusion Tooth anomaly Double tooth
2009/12/30
Fusion is a developmental anomaly defined as the union of two normally separated tooth buds or the partial splitting of one tooth bud into two buds. Depending on the stage of development, fusion may b...
Improved Image Fusion in PET/CT Using Hybrid Image Reconstruction and Super-Resolution
Improved Image Fusion PET/CT
2009/9/8
Purpose. To provide PET/CT image fusion with an improved PET resolution and better contrast ratios than standard reconstructions. Method. Using a super-resolution algorithm, several PET acquisitions w...
Experimental Study on Bioluminescence Tomography with Multimodality Fusion
Bioluminescence Tomography Multimodality Fusion
2009/9/7
To verify the influence of a priori information on the nonuniqueness problem of bioluminescence tomography (BLT), the multimodality imaging fusion based BLT experiment is performed by multiview noncon...
Registration and Fusion of the Autofluorescent and Infrared Retinal Images
Infrared Retinal Images Registration
2009/9/4
This article deals with registration and fusion of multimodal opththalmologic images obtained by means of a laser scanning device (Heidelberg retina angiograph). The registration framework has been de...
Treatment of Cervical Spondylosis by Anterior Subtotal Vertebrectomy and Iliac Bone Fusion
Cervical spondylosis myelopathy radiculopathy vertebrectomy
2009/7/1
There is no ideal surgical technique for cervical spondylosis. The choice of surgical procedure remains controversial. A series of 25 patients who had undergone subtotal vertebrectomy and iliac bone f...
Fusion of Medicine and Engineering for Biomedical Engineering in 21st Century
Medicine Engineering Biomedical Engineering
2009/6/1
Fusion of Medicine and Engineering for Biomedical Engineering in 21st Century.
Robust EMG sensing system based on data fusion for myoelectric control of a robotic arm
Robust EMG sensing system data fusion myoelectric control a robotic arm
2010/2/25
The fault robustness and safety characteristics of a myoelectric controlled manipulator system were substantially improved. The proposed scheme prevents potential risks for the operator, the equipment...