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A Comparison of Dexmedetomidine, Moxonidine and Alpha-Methyldopa Effects on Acute, Lethal Cocaine Toxicity
Cocaine Intoxication Dexmedetomidine Moxonidine Alpha-Methyldopa
2015/11/6
Background: The treatment of cocaine toxicity is an important subject for emergency physicians. We investigated the effects of dexmedetomidine, moxonidine and alpha-methyldopa on acute cocaine toxicit...
Chronic Ethanol Drinking by Alcohol-preferring Rats Increases the Sensitivity of the Mesolimbic Dopamine System to the Reinforcing and Stimulating Effects of Cocaine
alcohol ethanol cocaine dopamine mesolimbic nucleus accumbens ventral tegmental area VTA rat alcohol-preferring microdialysis intracranial ICSA
2015/1/9
Alcohol and cocaine are commonly co-abused drugs, and those meeting criteria for both cocaine and alcohol use disorders experience more severe behavioral and health consequences than those with a sing...
Design of Cocaethylene and Cocaine conjugates to produce highly selective Polyclonal Antibodies
cocaine cocaethylene benzoylecgonine hapten antibody
2009/4/20
With the aim to obtain specific anti-cocaine antibodies directed against cocaine and active metabolites for use in immunotherapy, a series of six haptens were prepared, based on the structure of ...
Effects of cocaine hydrochloride on reproductive function and sexual behavior of male rats and on the behavior of their offspring
cocaine hydrochloride reproductive function sexual behavior male rats offspring
2009/2/23
Cocaine hydrochloride (30, 15, or 0 mg/kg) was administered daily subcutaneously to male rats for a minimum of 72 days. Animals receiving the 15-mg/kg and 0-mg/kg doses were pair-fed with animals re...