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The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system
ECM (extracellular matrix) Hydrogel Mechanical properties Polyethylene oxide Smooth muscle cell
2010/1/7
Studies using 2-D cultures have shown that the mechanical properties of the extracellular matrix (ECM) influence cell migration, spreading,
proliferation, and differentiation; however, cellular mecha...
Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures
Scaffold Polyethylene glycol Hydrogel Mechanical properties Tissue engineering
2010/1/7
Tissue engineering scaffolds are fabricated from either biological materials, which provide biofunctional signals and interact well
with cells, or from synthetic polymers, which provide precise contr...
