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The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including MIT's Whitehea...
What makes the body of a person or any other organism work can for the most part be summed up in a word: proteins.These big molecules carry out almost all processes in living organisms, including movi...
Negative feedback is a universal control mechanism that lets a system’s output throttle its input. If an engine revs up, negative feedback tapers its power source. But if the engine slows down, it re-...
The protein complex that holds strands of DNA in compact spools partially disassembles itself to help genes reveal themselves to specialized proteins and enzymes for activation, according to Rice Univ...
Proteins are more than a dietary requirement. This diverse set of molecules powers nearly all of the cellular operations in a living organism. Scientists may know the structure of a protein or its fun...
Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to ...
This dissertation describes structure-function studies of CXXC finger protein 1 (Cfp1), encoded by the CXXC1 gene, in order to determine the functional significance of Cfp1 protein domains and propert...
Phosphorylation of eukaryotic initiation factor 2 (eIF2) is an important mechanism regulating global and gene-specific translation during different environmental stresses. Repressed global translation...
By combining two highly innovative experimental techniques, scientists at the University of Illinois at Urbana-Champaign have for the first time simultaneously observed the structure and the correlate...
The PRL family of enzymes constitutes a unique class of protein tyrosine phosphatase, consisting of three highly homologous members (PRL-1, PRL-2, and PRL-3). Family member PRL-3 is highly expressed i...

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