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The role of pyruvate dehydrogenase kinase in glucose and ketone body metabolism
ketoacidosis hypothermia fatty acid pyruvate carboxylase
2015/5/25
The expression of pyruvate dehydrogenase kinase (PDK) 2 and 4 are increased in the fasted state to inactivate the pyruvate dehydrogenase complex (PDC) by phosphorylation to conserve substrates for glu...
Regulation of glucose homeostasis by Doc2b and Munc18 proteins.
Diabetes SNARE proteins exocytosis
2015/5/25
Glucose homeostasis is maintained through the coordinated actions of insulin secretion from pancreatic beta cells and insulin action in peripheral tissues. Dysfunction of insulin action yields insulin...