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2017受精和激活发展高登研究研讨会（The Gordon Research Seminar(GRS) on Fertilization and Activation of Development）
2017 受精和激活发展高登研究 研讨会
2017/3/13
The Gordon Research Seminar (GRS) on Fertilization and Activation of Development offers a unique opportunity for junior researchers, such as graduate students, post-docs and early-career researchers, ...
2017“Fertilization&Activation of Development”戈登学术会议（The 2017 Gordon Research Conference on Fertilization&Activation of Development ）
2017 Fertilization&Activation of Development 戈登学术会议
2017/2/14
The union of egg and sperm creates a new totipotent cell – the zygote. In addition to starting the development of a new organism, fertilization also provides an excellent system in which to investigat...
Firing properties of dopamine neurons in freely moving dopamine-deficient mice:Effects of dopamine receptor activation and anesthesia
Firing properties dopamine neurons freely moving dopamine-deficient mice dopamine receptor activation and anesthesia
2015/8/7
To examine the regulation of midbrain dopamine neurons, recordings were obtained from single neurons of freely moving, genetically engineered dopamine-deficient (DD) mice. DD mice were tested without ...
The role of nitric oxide in parthenogenetic activation of pig oocytes: A review
oocyte parthenogenesis activation nitric oxide
2015/6/4
Parthenogenetic activation of mammalian oocytes with artificial stimuli is commonly applied in various reproductive biotechniques, e.g. cloning using nuclear transfer. For this reason, many studies fo...
Effects of protein kinase C on parthenogenetic activation of pig oocytes using calcium ionophore or nitric oxide-donor
oocyte pig parthenogenesis activation calcium ionophore nitric oxide
2015/6/4
Porcine oocytes matured in vitro were activated for parthenogenetic development using either calcium ionophore (50μM for 10 min) or nitric oxide donor SNAP (2mM for 23.5 hours). Protein kinase C (PKC)...
The influence of the Ku80 carboxy-terminus on activation of the DNA-dependent protein kinase and DNA repair is dependent on the structure of DNA cofactors
DNA-PK Ku70/80 Ku80 Carboxy Terminus
2015/5/25
In mammalian cells DNA double strand breaks (DSBs) are highly variable with respect to sequence and structure all of which are recognized by the DNA- dependent protein kinase (DNA-PK), a critical comp...
ADF/Cofilin Activation Regulates Actin Polymerization and Tension Development in Canine Tracheal Smooth Muscle
dissertations research thesis
2015/5/22
The contractile activation of airway smooth muscle tissues stimulates actin polymerization and the inhibition of actin polymerization inhibits tension development. Actin depolymerizing factor (ADF) an...
Molecular “hats” allow in vivo activation of disguised signaling peptides
Molecular hats vivo activation disguised signaling peptides
2014/12/30
When someone you know is wearing an unfamiliar hat, you might not recognize them. Georgia Institute of Technology researchers are using just such a disguise to sneak biomaterials containing peptide si...
Cloning and characterization of a new gene involved in lymphocyte activation
The immune system mouse models cow in vitro lymphocyte activation immunology lymphocyte activated gene
2014/12/11
Cattle represent an economically important species whose immune system seems to depart from the standard human and murine models. Little has been documented about bovine lymphocyte activation in vitro...
The role of Notch in T cell activation and development
To activate T cells incision p53 intracellular domain HES1 genes
2014/12/11
Notch is crucial for multiple stages of T cell development, including the CD4+CD8+ double positive (DP) to CD8 + single positive (SP) transition, but regulation of Notch activation is not well underst...
Notch-1 regulates IFN-gamma secretion through activation of NF-kappaB
An immune response cell factor cell differentiation T cells activate T cell line
2014/12/11
The cytokine IFN-γ is important in mediating immune responses, while the Notch family of transmembrane receptors has been implicated in modulating T cell differentiation at several stages of developme...
EGFR expression and activation in bovine cumulus cells and EGFR intramolecular regulation through interactions between tyrosines
Epidermal growth factor receptor the process of cell the cell cycle cell migration cell metabolism cell proliferation oocytes and embryo development activation of cumulus cells
2014/12/11
The epidermal growth factor receptor (EGFR) plays important roles in the control of many fundamental cellular processes including cell cycle, cell migration, cell metabolism and survival, cell prolife...
Notch functions from the cytoplasm to the nucleus during T cell activation
Cytokines T cells activate cells cell signal
2014/12/11
Notch1 specifically upregulates expression of the cytokine interferon-γ in peripheral T cells through activation of NF-κB. However, how Notch mediates NF-κB activation remains unclear. NF-κB activatio...
WC1 mediates T cell activation and is required for the response of bovine gammadelta T cells to Leptospira antigen
Biological sciences T cell activation Leptospira
2014/12/11
Workshop cluster 1 (WC1) molecules are exclusively expressed on the surface of γδ T cells. They belong to the scavenger receptor cysteine-rich (SRCR) superfamily and are encoded by a multiple-gene fam...
NON-CANONICAL NOTCH SIGNALING REGULATES ACTIVATION AND DIFFERENTIATION OF PERIPHERAL CD4+ T CELLS
Notch non-canonical T cell NF-kB mTOR activation differentiation cross-talk
2014/12/10
Cleavage of the Notch receptor via a γ-secretase, results in the release of the active intra-cellular domain of Notch that migrates to the nucleus and interacts with RBP-JΚ, resulting in the activatio...