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Structural and Spectroscopic Analysis of the Kinase Inhibitor Bosutinib and an Isomer of Bosutinib Binding to the Abl Tyrosine Kinase Domain
Humans Escherichia coli Benzamides Quinolines Nitriles Aniline Compounds Piperazines Pyrimidines Thiazoles Recombinant Proteins
2016/5/25
Chronic myeloid leukemia (CML) is caused by the kinase activity of the BCR-Abl fusion protein. The Abl inhibitors imatinib, nilotinib and dasatinib are currently used to treat CML, but resistance to t...
专著信息
书名
Theoretical identification of carbon clusters C20: prevalence of the monocyclic isomer and existences of the smallest fullerene and bowl isomer
语种
英文
撰写或编译
作者
Jing Lu,Suyong Re,Yoongkee Choe,S...
6-Apr-2007,LIVERMORE, Calif. -- Livermore researchers have moved one step closer to being able to turn on and off the decay of a nuclear isomer.