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Academy of Mathematics and Systems Science, CAS Colloquia & Seminars：Cross-linked Peptide Identification Using a Protein-feedback Method
蛋白质 反馈法 交联肽
2023/11/7
Improving the sensitivity of protein-protein interaction detection and protein structure probing is a principal challenge in cross-linking mass spectrometry (XL-MS) data analysis. In this talk, we pro...
New technologies reveal cross-cutting breakdowns in Alzheimer’s disease（图）
阿尔茨海默病 交叉细分 单细胞分析 脑细胞
2023/6/21
After decades of fundamental scientific and drug discovery research, Alzheimer’s disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But in a new review articl...
Academy of Mathematics and Systems Science, CAS Colloquia & Seminars：Data-Driven Production-Service Planning: Ambiguity Aversion, Service-Dependency and Cross-Product Heteroskedasticity
数据驱动 生产-服务规划 歧义厌恶 服务依赖 跨产品异端性
2023/5/8
We consider a joint production-service planning problem with demand uncertainty, where the manufacturer aims to determine the portfolio of products with the associated service levels and the capacity ...
中山大学骆观正团队利用CROss-seq技术系统鉴定多个CRISPR工具的脱靶效应（图）
骆观正 脱靶效应 基因编辑
2022/11/30
自从科学家们研究清楚CRISPR-Cas系统的作用机理并将其应用于真核细胞的基因编辑后，相关工具的开发、改造和应用呈爆发式增长，成为生物学研究的重要手段。目前主要的CRISPR编辑工具有Cas9、Base editor (BE)和Prime editor (PE)，及衍生的各种工具。CRISPR编辑工具在基因功能研究、转录调控、表观遗传修饰和基因治疗等众多研究领域具有重要应用和广阔前景。但是，CR...
Unlike electrons, quarks cannot wander freely in ordinary matter. They are confined by the strong force within hadrons such as the protons and neutrons that make up atomic nuclei. However, at very hig...
中国地质大学科学技术发展院陈孝君(博士研究生),姚光庆* 等, 资源学院/构造与油气资源教育部重点实验室 JGR-Solid Earth, 2019, Capillary Pressure Curve Determination Based on a 2‐D Cross‐Section Analysis Via Fractal Geometry: A Bridge Between 2‐D and 3‐D Pore Structure of Porous Media（图）
二维；多孔介质；三维；输运机理
2021/10/20
近日，国际地球物理Nature Index期刊《Journal of Geophysical Research: Solid Earth》刊出了中国地质大学关于多孔介质二维和三维之间输运机理方面的最新研究成果：基于分形几何的二维截面分析确定毛细管压力曲线：多孔介质的二维和三维孔隙结构之间的桥梁(Capillary Pressure Curve Determination Based on a 2-...
Executive functions and the ω-6-to-ω-3 fatty acid ratio: a cross-sectional study
fatty acids executive functions middle childhood CANTAB Electric Maze Task
2018/11/12
Background: The ω-6 (n–6) to ω-3 (n–3) fatty acid (FA) ratio (n–6:n–3 ratio) was previously shown to be a predictor of executive function performance in children aged 7–9 y.
Vitamin B-12 status and neurologic function in older people: a cross-sectional analysis of baseline trial data from the Older People and Enhanced Neurological Function (OPEN) study
neurologic older people vitamin B-12 peripheral conduction central nerve conduction
2018/12/14
Background: Aging is associated with a progressive decline in vitamin B-12 status. Overt vitamin B-12 deficiency causes neurologic disturbances in peripheral and central motor and sensory systems, but...
Carcass and Meat Quality Traits in an Embden×Toulouse Goose Cross Raised in Organic Dehesa
Carcass Organic Dehesa Fatty Acids Geese Meat Quality
2016/7/27
This study assessed the influence of genetic type (Embden-Anser anser, EE; Toulouse-Anser anser, TT and F1 cross, ET) for meat characteristics (carcass, meat quality and fatty acid (FA) profiles), of ...
Study of Genetic Diversity among Simmental Cross Cattle in West Sumatra Based on Microsatellite Markers
Simmental West Sumatra Microsatellite Genetic Diversity
2016/5/19
A study was conducted to assess the genetic diversity among Simmental Cross cattle in West Sumatra using microsatellite DNA markers. A total of 176 individual cattle blood samples was used for obtaini...
Associate Professor Raymond K. Cross，Department of Microbiology & Immunology at University of Maryland（图）
Associate Professor Raymond K. Cross Department of Microbiology & Immunology at University of Maryland
2015/12/31
Raymond K. Cross, Jr., M.D.,M.S. is a board certified Gastroenterologist and Associate Professor of Medicine, Division of Gastroenterology and Hepatology, at the University of Maryland School of Medic...
Leukocyte telomere length is related to appendicular lean mass: cross-sectional data from the Berlin Aging Study II (BASE-II)
appendicular lean mass BASE-II leukocytes muscle mass sarcopenia telomere length
2018/11/23
Background: Age-related progressive loss of muscle mass is an increasing problem in our aging society, affecting physical ability, risk of falls, and need for health care. Telomere length has been rec...
Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes.
Chemical cross-linking/mass spectrometry targeting acidic residues proteins protein complexes.
2015/12/11
The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years. Thus far,...
THE BACKWARD BEHAVIOR OF THE RICCI AND CROSS CURVATURE FLOWS ON SL(2,R)
THE RICCI CROSS CURVATURE FLOWS
2015/8/25
This paper is concerned with properties of maximal solutions of the
Ricci and cross curvature flows on locally homogeneous three-manifolds of type
SL2(R). We prove that, generically, a maximal solut...
Factor analysis is over a century old, but it is still problematic to choose
the number of factors for a given data set. The scree test is popular but subjective. The best performing objective method...