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New CRISPR-based tool inserts large DNA sequences at desired sites in cells（图）
CRISPR 新型工具 大DNA序列 PAST 基因工程
2023/6/21
Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.
Search Technique Helps Researchers Find DNA Sequences in Minutes Rather Than Days
Researchers DNA Sequences Minutes Rather Than Days
2016/2/23
Database searches for DNA sequences that can take biologists and medical researchers days can now be completed in a matter of minutes, thanks to a new search method developed by computer scientists at...
Researchers shed new light on regulation of repetitive DNA sequences
Researchers repetitive DNA sequences
2016/2/22
A pair of studies by a team of scientists has shed new light on the nature of a particular type of DNA sequences—tandem DNA repeat arrays—that play important roles in transcription control, genome org...
利用DNA序列构建系统树的方法介绍Introduction to the Methods of ConstructingPhylogenetic Trees with DNA sequences
系统树 距离法 简约法 大似然法 贝叶斯推断法
2008/1/10
摘要
利用DNA序列进行系统发生分析是分子进化研究的必要手段。构建系统树的方法有距离法、简约法、最大似然法以及贝叶斯推断法等。要解决特定的系统发生问题，首先要挑选合理的分类群及序列，尽量减少数据的偏倚，然后选择构树方法，最后还要对结果进行评价并给出进化学上的解释。本文讨论了挑选数据的原则及存在的问题，介绍了几种构树方法的基本原理及步骤，并列举了它们的优缺点。Abstract: Construct...
2002Vol.37No.5pp.637-640DOI:
Which Are More Random: Coding or Noncoding DNA Sequences?
WU Fang1 and ZHENG Wei-Mou2
1 Department of Physics, Peking University, Beijing 1...
9 million NHGRI award to University of Chicago team will enable genome-wide discovery of the DNA sequences that regulate genes（图）
Human Genome fruit fly
2007/5/25
May 15, 2007，The National Human Genome Research Institute, part of the National Institutes of Health, has awarded $9.1 million over four years to a research team led by the University of Chicago to id...
Electrochemical Detection of Specific DNA Sequences From PCR Amplicons on Carbon and Mercury Electrodes Using Meldola's Blue as an Intercalator
DNA Biosensor Meldola's Blue Intercalator PCR Hybridization
2010/4/20
The electrochemical parameters for 7--dimethyl--amino--1,2-- benzophenoxazinium Meldola's Blue, (MDB) on binding to DNA at both a hanging mercury drop electrode (HMDE) and carbon paste electrode (CPE)...