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染色质重塑主要包括围绕核小体的组蛋白修饰和染色质重塑蛋白介导的染色质构型调控。染色质重塑介导的基因转录表达调控是植物基因转录调控最重要的调控机制之一。然而,目前对于病原菌侵染诱导的寄主植物核小体动态变化及其与基因转录表达的关系尚不清楚。
褐飞虱是水稻生产中最严重的害虫。褐飞虱通过针状口器刺入水稻叶鞘组织吸食韧皮部汁液,造成水稻严重减产甚至绝收。种植抗性品种是综合防控褐飞虱的基础。然而植物抗病虫性通常受光照、温度和湿度等环境因素的影响,在一定程度上制约了抗性基因的有效利用。如采用密植的栽培方式是当前许多作物增加单位面积产量的重要途径,但是密植通常会导致冠层以下的植株部分光照不足而产生庇荫反应,易滋生各类病虫害,虽然这种现象普遍存在,...
MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria bec...
生长素在植物的正常生长发育中起着至关重要的作用。TAA/YUCCA基因家族编码色氨酸氨基转移酶(tryptophan aminotransferase),是生长素合成的关键酶。然而,棉花中YUCCA(YUC)基因家族尚未见报道。为了揭示YUC基因在棉花中的功能,我们系统地鉴定了五个棉种中的YUC基因家族,包括成员分析、特征描述、基因组内复制和共线关系。转录组学分析表明,GhYUCs参与了棉花的非生...
Strategies to reduce antibiotic prescribing in primary care are insufficient alone to halt the rise in drug resistant E. coli infections in England, a new report concludes.
A Northwestern University-led team funded by the National Science Foundation has developed BioBits, a suite of hands-on educational kits that enable students to perform a range of biological experimen...
Background: Emerging research suggests that redistributing total protein intake from 1 high-protein meal/d to multiple moderately high-protein meals improves 24-h muscle protein synthesis. Over time, ...
Background: Overweight and obese older people face a high risk of muscle loss and impaired physical function, which may contribute to sarcopenic obesity. Resistance exercise training (RET) has a benef...
Background: Overweight and obese older people face a high risk of muscle loss and impaired physical function, which may contribute to sarcopenic obesity. Resistance exercise training (RET) has a benef...
Background: To our knowledge, the effect of magnesium supplementation on blood pressure (BP) in individuals with preclinical or noncommunicable diseases has not been previously investigated in a meta-...
Background: Evidence has suggested that omega-3 (n–3) polyunsaturated fatty acids (PUFAs) improve obesity-induced insulin resistance (IR); however, results from human intervention trials have been equ...
Background: Obesity and associated metabolic disorders are related to impairments of the intestinal barrier. Objective: We examined lactulose:mannitol (Lac:Man) permeability in obese individuals with...
Background: S100 calcium-binding protein A9 (S100A9) has previously been identified as a type 2 diabetes (T2D) gene. However, this finding requires independent validation and more in-depth analyses in...
Background: It is unclear whether and at what dose vitamin D supplementation affects insulin resistance (IR).
Antibiotic-resistant bacteria most often are associated with hospitals and other health-care settings, but a new study indicates that chicken coops and sewage treatment plants also are hot spots of an...

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