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A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech development
Genetic disorders FOXP2 language barriers genome sequencing the children's speech apraxia
2018/3/5
Genetic investigations of people with impaired development of spoken language provide windows into key aspects of human biology. Over 15 years after FOXP2 was identified, most speech and language impa...
Early developmental gene enhancers affect subcortical volumes in the adult human brain
functional genomics gene enhancer GWAS hippocampus neurodevelopment subcortical volume
2016/5/3
Genome-wide association screens aim to identify common genetic variants contributing to the phenotypic variability of complex traits, such as human height or brain morphology. The identified genetic v...
Exploring human brain lateralization with molecular genetics and genomics
genomics genetics transcriptome neurodevelopment
2015/12/18
Lateralizations of brain structure and motor behavior have been observed in humans as early as the first trimester of
gestation, and are likely to arise from asymmetrical genetic–developmental ...
Modality-Independent Decoding of Semantic Information from the Human Brain
amodal FMRI multivoxel pattern analysis searchlight semantics
2015/5/6
An ability to decode semantic information from fMRI spatial patterns has been demonstrated in previous studies mostly for 1 specific input modality. In this study, we aimed to decode semantic category...
Assessing the effects of common variation in the FOXP2 gene on human brain structure
FOXP2 imaging genetics language transcription factor MRI brain anatomy VBM
2015/5/5
The FOXP2 transcription factor is one of the most well-known genes to have been implicated in developmental speech and language disorders. Rare mutations disrupting the function of this gene have been...
Context-dependent Semantic Processing in the Human Brain: Evidence from Idiom Comprehension
Semantic Processing Human Brain Idiom Comprehension
2015/4/24
Language comprehension involves activating word meanings and integrating them with the sentence context. This study examined whether these routines are carried out even when they are theoretically unn...
A Dissociation Between Linguistic and Communicative Abilities in the Human Brain
communication language mentalizing theory of mind neuroimaging
2015/4/8
Although language is an effective vehicle for communication, it is unclear how linguistic and communicative abilities relate to each other. Some researchers have argued that communicative message gene...
